{"id":1210,"date":"2023-06-16T11:25:44","date_gmt":"2023-06-16T11:25:44","guid":{"rendered":"https:\/\/hemdifferently-dev-001.azurewebsites.net\/en-gb\/?page_id=1210"},"modified":"2024-02-20T10:04:43","modified_gmt":"2024-02-20T10:04:43","slug":"what-are-the-risks-of-gene-therapy","status":"publish","type":"page","link":"https:\/\/haemophilia.biomarin.com\/en-gb\/what-are-the-risks-of-gene-therapy\/","title":{"rendered":"What are the POSSIBLE risks of gene therapy?"},"content":{"rendered":"
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What are the possible risks of gene therapy?\n<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n
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Many forms of gene therapy are being researched only in adults, at least initially<\/h2>\n

Some gene<\/span><\/strong> therapies won’t work in patients with certain antibodies or other pre-existing conditions. Gene therapy also comes with risks. Ongoing clinical trials are being conducted in people across many categories to determine the potential risks of treatment with gene therapy.<\/p>\n <\/div>\n \t\t<\/div>\n\t<\/div>\n<\/div>\n\n

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SAFETY IS A TOP PRIORITY<\/h2>\n

It’s important to understand that many safety precautions are being taken during the development of gene therapy. Clinical trials in the United States are closely monitored by the Food and Drug Administration and the National Institutes of Health. Based on an assessment by the FDA, there are more than 800 active gene therapy investigational new drugs currently on file with the FDA. Patient safety is the top priority. Ongoing clinical trials and research have identified some risks associated with gene therapy, and further research and experience may uncover additional risks that are currently unknown.<\/p>\n

POTENTIAL RISKS<\/h2>\n

Gene transfer that uses an adeno-associated virus<\/span><\/strong> (AAV) vector<\/span><\/strong> to deliver the new genetic material may have several risks:<\/p>\n